Fatty alcohol esters
Apexbio Technology LLC Megestrol Acetate 595-33-5 5g
Megestrol Acetate (CAS 595-33-5) is a synthetic progestin utilized to downregulate nuclear and cytoplasmic androgen receptor activity It modulates hormone receptor-mediated processes thereby impacting cellular metabolic and signaling pathways Megestrol Acetate exerts its biological activity primarily by inducing apoptosis and disrupting cell cycle progression In in vitro studies using HepG2 cell lines Megestrol Acetate demonstrates proliferation inhibition with an IC50 value of approximately 260 M Based on these pharmacological properties Megestrol Acetate holds research potential in studies of cancer cachexia hepatocellular carcinoma and the investigation of tumor growth mechanisms
Medchemexpress LLC Abiraterone acetate | 154229-18-2 | 99.9% | C26H33NO2 | 100 MG
Abiraterone acetate is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity. It is an ester prodrug of Abiraterone, an anticancer agent that inhibits key enzymes involved in steroidogenesis.
- Potent, selective, and irreversible inhibitor of CYP17A1.
- Exhibits antiandrogen activity.
- Functions as an ester prodrug of Abiraterone.
- Inhibits 17,20-lyase and 17α-hydroxylase.
- Suppresses proliferation of AR-positive prostate cancer cell lines.
- Blocks synthesis of 5α-dione and DHT.
- Inhibits CRPC progression and prolongs survival in castration-resistant prostate cancer.
Medchemexpress LLC Ziconotide acetate (SNX-111 acetate) | 914454-03-8 | 99.2% | 2639.13 (free base) | 1 MG
Ziconotide acetate (SNX-111 acetate) | 914454-03-8 | 99.2% | 2639.13 (free base) | 1 MG
Medchemexpress LLC CGGK acetate | 96.78% | 363.43 (free acid) | 1 MG
CGGK acetate is a control peptide of CAQK peptide, intended for research use only. It presents as a white to off-white solid with a purity of 96.78% and a molecular weight of 363.43 (free acid). Its chemical formula is C13H25N5O5S.xC2H4O2. This product is shipped at room temperature and requires sealed storage, away from moisture.
- Sequence: Cys-Gly-Gly-Lys
- Purity: 96.78%
- Solubility in DMSO: ≥ 100 mg/mL
- Powder storage: -80°C for 2 years, or -20°C for 1 year
- In solvent storage: -80°C for 6 months, or -20°C for 1 month
Medchemexpress LLC Poneratoxin acetate | 2756.35 (free base) | 10 MG
Poneratoxin acetate is the acetate salt form of Poneratoxin (HY-P10234). It acts as a modulator for voltage-gated sodium channels (NaV, with EC50 for NaV1.6 and NaV1.7 being 97 nM and 2.3 μM), decreasing the voltage threshold for activation and inhibiting channel inactivation. This compound enhances the excitability of neurons and contributes to the transmission of pain signals.
- Modulator for voltage-gated sodium channels
- Lowers the voltage threshold for activation
- Inhibits the inactivation of channels
- Enhances the excitability of neurons
- Contributes to the transmission of pain signals
- For powder, store at -80°C for 2 years or -20°C for 1 year
- For solution, store at -80°C for 6 months or -20°C for 1 month
- Store sealed and away from moisture
Medchemexpress LLC CBP-501 (acetate) | 1929.06 (free base) | 1 MG
CBP-501 acetate is a cell-permeable calmodulin-binding peptide and a G2-abrogating drug candidate. It inhibits the activity of multiple Ser216-specific kinases, including MAPKAP-K2, C-Tak1, CHK1, and CHK2. It is used for various types of cancer and enhances the cytotoxicity of CDDP and Bleomycin against cancer cells both in vitro and in vivo.
- Inhibits MAPKAP-K2 with an IC50 of 0.9 μM
- Inhibits C-Tak1 with an IC50 of 1.4 μM
- Inhibits Chk1 with an IC50 of 3.4 μM
- Inhibits Chk2 with an IC50 of 6.5 μM
- Stable for 2 years at -80°C as powder
- Stable for 1 year at -20°C as powder
- Stable for 6 months at -80°C in solvent
- Stable for 1 month at -20°C in solvent
- Enhances cytotoxicity of CDDP and Bleomycin
Medchemexpress LLC Goserelin (acetate) | 145781-92-6 | MFCD01747329 | 99.9% | C61H88N18O16 | 10MG
Goserelin (acetate) is a synthetic decapeptide analog of gonadotropin-releasing hormone (GnRH) used as a research-grade GnRH agonist for in vitro and in vivo studies of hormone-dependent cancers, reproductive biology, and endocrine signaling. Provided as the acetate salt with high analytical purity, it is supplied as a white to off-white solid and intended for research use only.
- Purity 99.9% (HPLC).
- Molecular formula C61H88N18O16 and molecular weight 1329.46.
- White to off-white solid suitable for analytical and biological assays.
- Supplied in small vial sizes suitable for dosing and assay development.
- Stable when stored sealed, away from moisture; powder: -80°C (up to 2 years), -20°C (up to 1 year).
- Acetate salt form for standard biochemical handling.
- For research use only; not for human or veterinary use.
Medchemexpress LLC Delmitide acetate 10mg | 501019-16-5 | 10MG
Delmitide (RDP58) acetate is an orally active d-isomer decapeptide with potent anti-inflammatory activity Delmitide acetate inhibits production of TNF- IFN- and interleukin (IL)-12 and up-regulates heme oxygenase 1 activity Delmitide acetate can be used for the research of ulcerative colitis[1 [2
Medchemexpress LLC (+)-Bornyl acetate | 20347-65-3 | MFCD00135942 | 98.0% | 196.29 g·mol⁻¹ | C12H20O2 | 10 MG
(+)-Bornyl acetate is a naturally occurring monoterpene ester found in pichtae (Siberian fir needle) essential oil. Supplied as a research-grade reagent with reported biological activity including inhibition of Arabidopsis root growth, it is used in aroma, flavor, and plant physiology studies. Typical properties include CAS 20347-65-3, molecular formula C12H20O2, molecular weight 196.29 g·mol⁻¹, and reported purity 98%.
- Natural monoterpene ester found in fir needle essential oil.
- Reported to inhibit root growth in Arabidopsis seedlings.
- High purity suitable for research applications (98%).
- Supplied in small, precise quantities appropriate for analytical and biological assays.
- Volatile aroma compound with applications in flavor and fragrance research.
- Applicable to plant physiology and bioactivity studies.
Apexbio Technology LLC Nafarelin Acetate 76932-56-4 50mg
Nafarelin Acetate is a synthetic agonist targeting gonadotropin-releasing hormone (GnRH) receptors It is designed to modulate the hypothalamic-pituitary-gonadal axis by initially stimulating and subsequently downregulating GnRH receptors in the pituitary gland thereby suppressing secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) Nafarelin Acetate exerts its biological activity primarily through receptor downregulation and suppression of pituitary hormone release Based on these pharmacological properties Nafarelin Acetate holds research potential in the investigation of endocrine signaling pathways associated with reproductive development disorders including central precocious puberty and endometriosis
Apexbio Technology LLC GERANYL-ACETATE-100MG
Geranyl acetate (CAS No 105-87-3) is a monoterpene ester commonly explored in biomedical research due to its natural occurrence in essential oils of plants like lemongrass and sweet marjoram It is primarily studied for its potential role in modulating cellular pathways involved in anti-inflammatory and anticancer activities Geranyl acetate exhibits in vitro activity in the nanomolar to low micromolar range which indicates its potency in biological systems Typical applications include cell-based assays and animal studies for drug screening and understanding its pharmacodynamics Experimental concentrations typically depend on the specific research design Researchers leverage its capability to impact signaling pathways like NF- B and MAPK which are crucial in inflammation and cancer development These studies aim to uncover therapeutic potentials and safety profiles contributing to developing novel treatments for various conditions